Endocrine Abstracts

Introduction: Fibroblast growth factor-21 (FGF-21) is a recently discovered hormone acting as a central regulator of metabolism via adaptation of glucose homeostasis, insulin sensitivity, and ketogenesis. While acute systemic inflammatory conditions come along with profound alterations of metabolism, the role of FGF-21 in these acute phase responses is still unknown.Methods: This is a secondary analysis of two randomized, controlled trials in patients pr...